Supplementary Note 6

First, there is crossing-over with the X-chromosome in the pseudoautosomal regions (aggregate length 3.0 Mb)1-5. 

1.            Simmler, M. C. et al. Pseudoautosomal DNA sequences in the pairing region of the human sex chromosomes. Nature 317, 692-697 (1985).

2.            Cooke, H. J., Brown, W. R. & Rappold, G. A. Hypervariable telomeric sequences from the human sex chromosomes are pseudoautosomal. Nature 317, 687-692 (1985).

3.         Freije, D., Helms, C., Watson, M. S. & Donis-Keller, H. Identification of a second pseudoautosomal region near the Xq and Yq telomeres. Science 258, 1784-1787 (1992).

4.            Kvaloy, K., Galvagni, F. & Brown, W. R. A. The sequence organization of the long arm pseudoautosomal region of the human sex chromosomes. Hum. Mol. Genet. 3, 771-778 (1994).

5.         Ried, K. et al. Characterization of a YAC contig spanning the pseudoautosomal region. Genomics 29, 787-792 (1995).