Supplementary Information for

Text

• Supplementary Discussion   
• Materials and Methods  
• References  

Figures

• Supplementary Figure 1   Re-analysis of single cell RNA-seq from human embryos
• Supplementary Figure 2   The induced gonadal program distinguishes germ cells from other lineages
• Supplementary Figure 3   Expression of genes activated on PGC colonization, and of general and naïve pluripotency factors in the mammalian germline
• Supplementary Figure 4   Dazl is necessary for germ cell commitment in diverse strains of mice
• Supplementary Figure 5   Requirement for Dazl in diverse strains of mice
• Supplementary Figure 6   Rate of spontaneous teratoma formation in mice
• Supplementary Figure 7   Generation of conditional Dazl allele in mice

Tables

• Supplementary Table1   Efficiency of EG cell derivation, analyzed by sex
• Supplementary Table2   SNP genotyping of teratomas in 129SF1.Dazl-deficient mice
• Supplementary Table3   Genotyping of TALEN-mediated deletions in pigs
• Supplementary Table4   Aggregated numbers of mice with spontaneous gonadal teratomas
• Supplementary Table5   Sample IDs for human GTEx data
• Supplementary Table6   Oligo and TALEN sequences used

Datasets

• Dataset 1   RNA-seq analysis of mouse germline from E9.5 to E11.5
• Dataset 2   Genes up-regulated following PGC colonization of the nascent gonads in mouse, and human one-to-one orthologs
• Dataset 3   Single-cell RNA-seq analysis of human germline as PGCs colonize the nascent gonads
• Dataset 4   Identification of SNPs that distinguish between 129S2 and 129S4 substrains