Supplementary Information

Supplementary Information for

Blanton LV, San Roman, AK, Wood G, Buscetta A, Banks N, Skaletsky H, Godfrey AK, Pham TT, Hughes JF, Brown LG, Kruszka P, Lin AE, Kastner KL, Muenke M, Page DC

Stable and robust Xi and Y transcriptomes drive cell-type-specific autosomal and Xa responses in vivo and in vitro in four human cell types

Document S1: Figures S1-S16
Table S1: Description of euploid and aneuploid donors, related to Figure 1
Table S2: NPX and PAR gene linear regressions to Xi or Chr Y dosage, related to Figures 1 and S3
Table S3: NPY gene linear regressions to Xi or Chr Y dosage, related to Figures 1 and S3
Table S4: Autosomal linear regressions to Xi or Chr Y dosage, related to Figure 3
Table S5: Autosomal linear regressions to Xi or Chr Y dosage, controlling for age, related to Figures 3 and S10
Table S6: Gene set enrichment results for CD4+ T cells, related to Figures 5, S13, and S14
Table S7: Gene set enrichment results for monocytes, related to Figures 5, S13, and S14
Table S8: Samples from in vitro CD4+ T cell activation, related to Figures 5 and S15
Table S9: Autosomal linear regressions to Xi of in vitro unstimulated and stimulated CD4+ T cells, related to Figures 5 and S15
Table S10: Gene set enrichment results for in vitro unstimulated and stimulated CD4+ T cells, related to Figure 5
Table S11: Deming regression and Pearson correlation statistics between response to Xi vs. Chr Y of Hallmark functional pathways (restricted to leading edge genes), related to Figure 5